If you've ever been told that progesterone “doesn’t matter” unless you have a uterus… or that your symptoms after starting progesterone HRT must mean “your dose is too high”… or that transdermal progesterone doesn’t work—then this article is for you.

If you’ve ever thought about hormone therapy but immediately felt a wave of fear—because you were told it causes cancer—you’re not alone. One of the most common things I hear from women is: “I was told I can’t do hormones because of breast cancer,” Or, “My doctor said hormones are dangerous—especially with my family history.”

Progesterone plays a critical role in balancing estrogen’s effects on the uterine lining. In a normal menstrual cycle: Estrogen builds up the uterine lining (called the proliferative endometrium). Progesterone comes in after ovulation and stabilizes and matures that lining, converting it into a secretory endometrium—a plush, nutrient-rich environment ready for a fertilized egg to implant.

Methylation is basically your body adding a small chemical group (one carbon + three hydrogens = a “methyl group”) to another molecule. Sounds tiny. But that little shift can completely change how your body functions.

You’ve probably heard people talk about estrogen like it’s either the hero or the villain when it comes to women’s health, especially breast cancer. The truth is, this area of women’s health is full of complexity, outdated research, and evolving science. But it’s also important. Because the way your body breaks down estrogen—your estrogen metabolism—can influence everything from mood and energy to long-term risks like breast cancer.

PMS (pre-menstrual syndrome) refers to a group of physical and emotional symptoms that a woman may experience in the week or so leading up to the beginning of her menstrual cycle (when she starts menstrual bleeding) and subsides within a few days of menstruation.  

There are two types of estrogen therapy, local estrogen therapy and systemic estrogen therapy.

When it comes to hormone balance, the goal is to achieve “Goldilocks” hormone levels ~ that is, not too much, not too little, just right levels of hormones.  Each woman is unique, which means she will thrive and feel best when hormones are at her own unique “Goldilocks” levels.