About Jim Hrncir, RPh

Jim Hrncir, RPh founded Las Colinas Pharmacy, Compounding & Wellness in 1984.  Recognized as one of the pioneers of modern pharmaceutical compounding, Jim’s 1986 creation of Estradiol Transdermal Gel was the first of its kind in the United States.  He is responsible for the formulation of many Bio-Identical Hormone, Dermatological, Nutritional, and Anti-Aging compounds in wide use throughout the United States.  Jim was named the 2017 Compounding Pharmacist of the Year by Professional Compounding Centers of America (PCCA) and Independent Pharmacist of Year 2022 by Pharmacy Development Services (PDS).   He served on the board of the International Academy of Compounding Pharmacists (IACP).  NCPA’s magazine America’s Pharmacist featured Jim and Las Colinas Pharmacy as the cover story for December 2019.  Las Colinas Pharmacy has been a PCAB/ACHC Accredited Compounding pharmacy since 2014.  Jim acts as a compounding pharmacy expert consultant for the Texas State Board of Pharmacy’s USP 800 task force and the Compounding Standards & Ethics task force.

The internationally syndicated Dr. Phil Show featured Jim on several episodes as an expert in Bio-Identical Hormones and Pharmaceutical Compounding.  Dr Phil’s Wife, Robin McGraw, promoted Jim’s Anti-Aging Skin Care product- Vitamin C Infusion Cream on separate episodes.  In Robin’s latest book What’s Age Got to Do With It?, Jim contributed the chapter on Hormones and Thyroid (proclaimed by Oprah as her “favorite chapter!”).    Dr Phil and Robin recruited Jim to help develop her Anti-Aging skin care line, Revelation, released in Nov 2016.

Optimum Integrative Medicine Patient Assessment and Management Software.  Utilizing a team of integrative medicine specialists, Jim spearheaded the development of a software program used by Integrative Medicine providers and Consulting Pharmacists to better assess, manage and treat female and male BHRT, thyroid and functional medicine cases.  The software also makes recommendations for supplements based on support of medical conditions and drug-induced nutrient depletions.  Jim continues to provide extensive integrative medicine clinical patient consultations for patients, for prescribing practitioners and is passionate about his work with veterans with Traumatic Brain injury utilizing the software.

Optimum Therapeutic Solutions (OTS)- professional use supplement line.  With nutrition and supplements occupying such an important place in his practice, Jim and his team developed an exclusive line of supplements, employing only the highest quality and research-based formulas.  The team also developed a web service that uses algorithmic logic to make supplement recommendations based on support of medical conditions (ICD-10 codes) or drug-induced nutrient depletions.  API/plug-ins to the web-service are set up for OHB software, OTS e-store, and for various pharmacy management softwares.  The line is only available to pharmacists and medical providers, via wholesale or through revenue sharing sales on the OTS e-store.

In demand to train physicians, mid-level medical providers, nurses and pharmacists, Jim provides a 9 contact hour course entitled “Nuts and Bolts Training for Bio-Identical Hormones, Thyroid and Anti-Aging Medicine”.  Providers receive intense, real-time, “how to practice” information on BHRT for Males, BHRT for Females, Thyroid, Low Dose Naltrexone, Adult Growth Hormone Deficiency, Ethical Nutritional Supplements, and Principles of Anti-Aging Medicine.

Jim has received extensive continuing education in the areas of Bio-Identical Hormones, Nutrition, Anti-Aging Medicine, Weight Management, Pain Management, Neurotransmitter Management, Brain Health, Natural and Functional Medicine including the use of botanical medicines, nutritional supplements, detoxification and purification, homeopathy and lab testing.   He has lectured across the country on a variety of topics including Clinical Patient Consulting, BHRT Assessment and Case Management, Low Dose Naltrexone, Traumatic Brain Injury Treatment Protocols, and Ketamine for Treatment-Resistant Depression and PTSD.

Using his advanced knowledge of integrative medicine, Jim developed treatment protocols to help patients suffering from Traumatic Brain Injury and subsequent downstream sequala including PTSD, depression, suicide ideation, social isolation disorders, self-medicating behaviors, and cognitive dysfunction.  Working with several veteran support groups, Jim has treated more than 200 veterans suffering from TBI and PTSD.

Jim is a member of Professional Compounding Centers of America (PCCA), American Academy of Anti-Aging Medicine, Age Management Medical Group, Texas Pharmaceutical Association, Alliance for Pharmacy Compounding, and the National Association of Community Pharmacists.

Highlights

• Compounding pharmacists are chemistry specialists who can customize prescriptions for men, women, and pets – there isn’t a one size fits all approach to HRT, and this is where compounding pharmacists shine.
• Customized compounded bioidentical hormones are a safer option than commercial formulations.
• HRT has been shown to decrease the risk of breast cancer, heart attack, and stroke dating back to the 1990s. Unfortunately, the Women’s Health Initiative (WHI) changed all that when the WHI’s lead researcher, Dr. Jacques Rossouw MD, released a false statement stating that there was an increased risk of breast cancer when it was not true. This statement has since been retracted, but women and many doctors remain afraid of estrogen today.
• Drug companies cannot patent anything made in the human body, so they cannot patent bioidentical hormones; hence they promote FDA-approved HRT, which are often synthetic or made with chemicals and are not customizable to a woman’s unique needs.
• Drug companies have pressured the FDA to ban bioidentical hormones to maintain the market share of HRT sales; women must use their voices and stand up for BHRT.
• Our bodies often need to start hormones low and slow. For women who have been off hormones or post-menopausal for a while without HRT, their receptor sites have to open back up to get ready to receive hormone signals.
• When using HRT, it’s important to keep hormone balance in mind. If you are using a low dose of estrogen, you likely want also to use a low dose of progesterone to ensure balance.
• Testosterone is necessary for women and has many benefits. A typical testosterone dose is around 2.5 mg transdermally applied to the skin and only 1 mg if applied labially because it absorbs more readily when applied to the labia. These doses will typically bring a woman whose testosterone was in the teens or twenties up to levels in the 40s.
• Testosterone pellets are not recommended because they deliver supraphysiologic doses of testosterone, and women often wind up with unwanted symptoms. Jim talks about the steroid euphoria women experience, which eventually wears off and makes women feel miserable.
• The importance of having proper levels of sex hormone binding globulin (SHBG) and albumin in the blood, which are proteins that transport hormones through the blood; Jim refers to albumin as the passenger bus and SHBG as the prisoner bus. A healthy SHBG for women is between 70 and 120.
• The base used in your HRT prescription matters. Jim typically uses Versabase for estrogen preparations and Atrevis Hyrdogel for testosterone absorption because it absorbs 2.7 times better than other bases for testosterone.
• Hormones are in two size categories: micronized, which is 30 to 50 microns, or super micronized, which is five to 10 microns. The size of the hormone makes a significant difference from an absorption perspective.
• When getting HRT filled, women should ask the pharmacist to show them the certificate of analysis of the chemical of the hormone to ensure they are getting a prescription that will properly absorb.
• It’s important to rotate the site of the application. If you continue to apply in the same area over and over, the hormones will build up in the subcutaneous fat layer, eventually inhibiting absorption.
• Jim shares some tips for quality of life and longevity

Links 

• Las Colinas Pharmacy, Compounding & Wellness
• Share your HRT testimony to protect your access to BHRT – We encourage women to go to Compounding.com to share a testimonial of how bioidentical hormones have helped them.